N-methoxy-N-methyl-4-nitrobenzamide → (1-Methyl-1H-imidazol-5-yl)(4-nitrophenyl)methanone

HRID 928746

Reaktionsgleichung

Reaktionsgleichung von HRID 928746
CON(C)C(C1SC=NC=1)=O.CON(C)[C:15](=[O:25])[C:16]1[CH:21]=[CH:20][C:19]([N+:22]([O-:24])=[O:23])=[CH:18][CH:17]=1.[CH3:27][N:28]1[C:32](C(C2SC=NC=2)=O)=[CH:31][N:30]=[CH:29]1>>[CH3:27][N:28]1[C:32]([C:15]([C:16]2[CH:17]=[CH:18][C:19]([N+:22]([O-:24])=[O:23])=[CH:20][CH:21]=2)=[O:25])=[CH:31][N:30]=[CH:29]1

Komponenten

4

Edukt 3

HCID 2991007N-methoxy-N-methyl-4-nitrobenzamideHCID 25307138N-Methoxy-N-methyl-1,3-thiazole-5-carboxamideHCID 86715592(1-Methyl-1H-imidazol-5-yl)(thiazol-5-yl)methanone2×

Produkt 1

HCID 86715600(1-Methyl-1H-imidazol-5-yl)(4-nitrophenyl)methanone

Versuchsvorschrift

The title compound was prepared by substituting N-methoxy-N-methylthiazole-5-carboxamide (Intermediate 11: step a) with N-methoxy-N-methyl-4-nitrobenzamide (Intermediate 20: step a) then following the procedure described for the preparation of (1-methyl-1H-imidazol-5-yl)(thiazol-5-yl)methanone (Intermediate 13).

Quellen und Nachweise

ORD-Eintrag
ord-e4a3596e0f244584b74197e096f27796
Quelldatensatz
uspto-grants-2016_03
Patentnummer
US09290476B2

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