3,4-Dichlorobenzeneboronic acid → 3',4'-Dichloro-5-(trifluoromethyl)-[1,1'-biphenyl]-2-ol
Reaktionsgleichung
C(C1C=C(C=O)C(O)=C(C2C=CC(OC(F)(F)F)=CC=2)C=1)(C)(C)C.Br[C:26]1[CH:31]=[C:30]([C:32]([F:35])([F:34])[F:33])[CH:29]=[CH:28][C:27]=1[OH:36].[Cl:37][C:38]1[CH:39]=[C:40](B(O)O)[CH:41]=[CH:42][C:43]=1[Cl:44]>>[Cl:37][C:38]1[CH:39]=[C:40]([C:26]2[C:27]([OH:36])=[CH:28][CH:29]=[C:30]([C:32]([F:35])([F:34])[F:33])[CH:31]=2)[CH:41]=[CH:42][C:43]=1[Cl:44]Komponenten
4
Versuchsvorschrift
3′,4′-Dichloro-5-(trifluoromethyl)-[1,1′-biphenyl]-2-ol was prepared as a yellow oil using the procedure described in Intermediate 5 from 2-bromo-4-(trifluoromethyl)phenol (Tetrahedron 2003, 59, 6545) and 3,4-dichlorophenylboronic acid.