Bromine → 6-Amino-5-bromopyridine-3-carbonitrile

Beteiligte Stoffe

Reaktionsschritte

To a solution of 6-aminonicotinonitrile (5.0 g) in acetic acid (50 mL) was added bromine (4.3 mL) under ice-cooling. The reaction mixture was stirred at room temperature for 3 days, and the precipitate was collected by filtration. The obtained solid was suspended in ethyl acetate and IPE, and collected by filtration to give the title compound (8.2 g).

Herkunft & Nachweise