2-Chloro-4-fluorophenacyl bromide → 5-(2-Chloro-4-fluorophenyl)-7-methyl-4-(1H-1,2,4-triazol-1-yl)imidazo[5,1-f][1,2,4]triazine
Reaktionsgleichung
FC1C=CC=CC=1C1[N:9]=[C:10]([CH3:22])[N:11]2C=1[C:15]([N:17]1[CH:21]=[N:20][CH:19]=[N:18]1)=[N:14][CH:13]=[N:12]2.Br[CH2:24][C:25]([C:27]1[CH:32]=[CH:31][C:30]([F:33])=[CH:29][C:28]=1[Cl:34])=O>>[Cl:34][C:28]1[CH:29]=[C:30]([F:33])[CH:31]=[CH:32][C:27]=1[C:25]1[N:9]=[C:10]([CH3:22])[N:11]2[C:24]=1[C:15]([N:17]1[CH:21]=[N:20][CH:19]=[N:18]1)=[N:14][CH:13]=[N:12]2Komponenten
3
Versuchsvorschrift
5-(2-Chloro-4-fluorophenyl)-7-methyl-4-(1H-1,2,4-triazol-1-yl)imidazo[5,1-f][1,2,4]triazine was prepared in similar fashion to C6 in Example 1, by employing 2-bromo-1-(2-chloro-4-fluorophenyl)ethanone.
Quellen und Nachweise
- ORD-Eintrag
- ord-0ee65ec9dde64302ad1091a470f6c15d
- Quelldatensatz
- uspto-grants-2016_03