5-Bromo-7-chloro-2-methylquinolin-6-ol → 5-Bromo-2,7-dimethylquinolin-6-ol
Reaktionsgleichung
[Br:1][C:2]1[C:11]([OH:12])=[C:10](Cl)[CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6]([CH3:14])=[N:7]2.[CH3:15]C1C=CC2C(=CC(C)=C(O)C=2)N=1>>[Br:1][C:2]1[C:11]([OH:12])=[C:10]([CH3:15])[CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6]([CH3:14])=[N:7]2Komponenten
3
Versuchsvorschrift
Compound 2C was prepared following the procedure used to prepare compound 1D of Example 1, except that 2,7-dimethylquinolin-6-ol (2B) was used instead of compound 1C. LCMS-ESI+ (m/z): 252.2, 254.2 (M+H)+.
Quellen und Nachweise
- ORD-Eintrag
- ord-627ad1fbc556470fa3d5d3e6e4e12fdd
- Quelldatensatz
- uspto-grants-2016_03
- Patentnummer
- US09296758B2
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