7-Methylquinolin-6-ol → 5-Bromo-6-hydroxy-7-methyl-quinoline
Reaktionsgleichung
[Br:1][C:2]1[C:11]([OH:12])=[C:10](Cl)[CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](C)=[N:7]2.[CH3:15]C1C=C2C(C=CC=N2)=CC=1O>>[Br:1][C:2]1[C:11]([OH:12])=[C:10]([CH3:15])[CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2Komponenten
3
Versuchsvorschrift
Compound 3D was prepared following the procedure used to prepare compound 1D of Example 1, except that 7-methylquinolin-6-ol (3C) was used instead of compound 1C. LCMS-ESI+ (m/z): 238.1, 240.1 (M+H)+.
Quellen und Nachweise
- ORD-Eintrag
- ord-a82bd784676e469995b92ed214ef52b0
- Quelldatensatz
- uspto-grants-2016_03
- Patentnummer
- US09296758B2
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