5-Bromo-6-hydroxy-7-methyl-quinoline → 5-(4-Chlorophenyl)-7-methylquinolin-6-ol
Reaktionsgleichung
Cl[C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][C:8](C)=[N:9]2)=[C:4]([C:13]2[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=2)[C:3]=1[OH:20].Br[C:22]1C(O)=C(C)C=C2C=1C=CC=N2>>[Cl:19][C:16]1[CH:15]=[CH:14][C:13]([C:4]2[C:3]([OH:20])=[C:2]([CH3:22])[CH:11]=[C:10]3[C:5]=2[CH:6]=[CH:7][CH:8]=[N:9]3)=[CH:18][CH:17]=1Komponenten
3
Versuchsvorschrift
Compound 3E was prepared following the procedure used to prepare compound 1E of Example 1, except that 5-bromo-7-methylquinolin-6-ol (3D) was used instead of compound 1D.
Quellen und Nachweise
- ORD-Eintrag
- ord-90efb87ef0a54dc581686461033694ee
- Quelldatensatz
- uspto-grants-2016_03
- Patentnummer
- US09296758B2
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