3-(7-Isopropylpyrido[2,3-d]pyrimidin-4-ylamino)-4-(4-(methoxycarbonylamino)phenylthio)benzoic acid → Methyl 4-(4-(1-(di-tert-butoxyphosphoryloxy)-2-phenylpropan-2-ylcarbamoyl)-2-(7-isopropylpyrido[2,3-d]pyrimidin-4-ylamino)phenylthio)phenylcarbamate

Reaktionsgleichung

[CH:24]([CH3:25])([CH3:26])[c:27]1[cH:28][cH:29][c:30]2[c:31]([n:32][cH:33][n:34][c:35]2[NH:36][c:37]2[cH:38][c:39]([C:40](=[O:41])[OH:42])[cH:43][cH:44][c:45]2[S:46][c:47]2[cH:48][cH:49][c:50]([NH:53][C:54](=[O:55])[O:56][CH3:57])[cH:51][cH:52]2)[n:58]1.[P:1](=[O:2])([O:3][CH2:4][C:5]([CH3:6])([c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[NH2:13])([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23]>>[P:1](=[O:2])([O:3][CH2:4][C:5]([CH3:6])([c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[NH:13][C:40]([c:39]1[cH:38][c:37]([NH:36][c:35]2[c:30]3[cH:29][cH:28][c:27]([CH:24]([CH3:25])[CH3:26])[n:58][c:31]3[n:32][cH:33][n:34]2)[c:45]([S:46][c:47]2[cH:48][cH:49][c:50]([NH:53][C:54](=[O:55])[O:56][CH3:57])[cH:51][cH:52]2)[cH:44][cH:43]1)=[O:41])([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23]