Tetrahydrofuran → tert-butyl 2-(difluoromethyl)-1-[4-(4-{[2-(dimethylamino)ethyl]sulfonyl}-1-piperazinyl)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]-4-methoxy-1H-benzimidazol-6-ylcarbamate

HRID 958180Notizen

Reaktionsgleichung

[CH2:57]1[O:58][CH2:59][CH2:60][CH2:61]1.[CH3:36][N:37]([CH2:38][CH2:39][S:40](=[O:41])(=[O:42])[N:43]1[CH2:44][CH2:45][NH:46][CH2:47][CH2:48]1)[CH3:49].[CH3:50][CH2:51][N:52]([CH2:53][CH3:54])[CH2:55][CH3:56].[Cl:1][c:2]1[n:3][c:4](-[n:14]2[c:15]([CH:33]([F:34])[F:35])[n:16][c:17]3[c:18]2[cH:19][c:20]([NH:25][C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[cH:21][c:22]3[O:23][CH3:24])[n:5][c:6]([N:8]2[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[n:7]1>>[c:2]1([N:46]2[CH2:45][CH2:44][N:43]([S:40]([CH2:39][CH2:38][N:37]([CH3:36])[CH3:49])(=[O:41])=[O:42])[CH2:48][CH2:47]2)[n:3][c:4](-[n:14]2[c:15]([CH:33]([F:34])[F:35])[n:16][c:17]3[c:18]2[cH:19][c:20]([NH:25][C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[cH:21][c:22]3[O:23][CH3:24])[n:5][c:6]([N:8]2[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[n:7]1