1-(4-Acetylamino-5-chloro-2-methoxyphenyl)-5-(piperidin-1-yl)pentan-1-one → 1-(4-Amino-5-chloro-2-methoxyphenyl)-5-(piperidin-1-yl)pentan-1-one hydrochloride

Beteiligte Stoffe

Reaktionsschritte

1-(4-Acetylamino-5-chloro-2-methoxyphenyl)-5-(piperidin-1-yl)pentan-1-one was dissolved in 2N hydrochloric acid (25 mL) and the solution was stirred for 30 minutes. The solution was cooled in an ice bath to form a precipitate. The precipitate was collected by filtration and washed with water. Drying in a vacuum oven at 70° C. gave 1-(4-amino-5-chloro-2-methoxyphenyl)-5-(piperidin-1-yl)pentan-1-one hydrochloride (0.65 g, 2 mmol), m.p. 220°-221° C.

Herkunft & Nachweise