8-Azido-1-octanol → 8-Amino-1-octanol
Reaktionsgleichung
[N:1]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][OH:12])=[N+]=[N-]>C(O)C.[Pd].CC([O-])=O.CC([O-])=O.[Pb+2]>[NH2:1][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][OH:12]Komponenten
4
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
8-Azido-octan-1-ol (1.99 g, 11.6 mmol) was dissolved in ethanol (25 mL) and Lindlar catalyst (200 mg) was added. The solution was hydrogenated at 50 psi, 30° C. for 2 hours. The catalyst was removed by filtration through Kieselguhr and the solvent was removed in vacuo to give a white solid 1.33 g (79% yield), mp 48°-53° C.;
Aufarbeitung
- customThe catalyst was removed by filtration through Kieselguhr
- customthe solvent was removed in vacuo
Quellen und Nachweise
- ORD-Eintrag
- ord-2b16e87c22f24a0daa7f2da642e7c306
- Quelldatensatz
- uspto-grants-1998_06
- Patentnummer
- US05767088
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