HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Hydroxide → {2-Nitro-5-[(undec-10-en-1-yl)oxy]phenyl}methanol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | Silane | HCID 23953 | — |
| Edukt | 3-(Hydroxymethyl)-4-nitrophenol | HCID 108946 | — |
| Edukt | Undecylenic bromide | HCID 21705948 | — |
| Katalysator | Benzenemethanaminium, N,N,N-tributyl-, bromide | HCID 2724282 | — |
| Produkt | {2-Nitro-5-[(undec-10-en-1-yl)oxy]phenyl}methanol | HCID 19074081 | — |
Reaktionsschritte
Synthesis of a o-nitrobenzyl PEG-silane of the above formula wherein R3 is H and m=11 was achieved in three steps. First, 5-hydroxy-2-nitrobenzyl alcohol I in 0.3 NaOH was refluxed for four days with undecylenic bromide II (dissolved in CH2Cl2) in the presence of benzyltributylammonium bromide to form 2-nitro-5-(10-undecenyloxy)phenylmethanol III according to the following reaction scheme: ##STR6##
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05773308 |
| Quelldatensatz | uspto-grants-1998_06 |
| ORD ID | ord-4e4e5ae11cbe458e8e3a31c676e798a5 |
| Quellennotiz | uspto-grants-1998_06 |