Hydrochloric Acid → Methyl 3-hydroxy-4,5-dimethoxybenzoate

HRID 967423Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 967423
[OH:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([O:13][CH3:14])[C:10]=1[O:11][CH3:12])[C:5]([OH:7])=[O:6].Cl.[CH3:16]O>>[CH3:16][O:6][C:5](=[O:7])[C:4]1[CH:8]=[C:9]([O:13][CH3:14])[C:10]([O:11][CH3:12])=[C:2]([OH:1])[CH:3]=1

Komponenten

4

Edukt 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 747093-Hydroxy-4,5-Dimethoxybenzoic Acid

Produkt 1

HCID 2733956Methyl 3-hydroxy-4,5-dimethoxybenzoate

Versuchsvorschrift

5 g (27.2 mmol) of 3-Hydroxy-4,5-dimethoxy-benzoic acid was added at 0° C. to 100 ml of a saturated solution of HCl in MeOH. The solution was stirred for 16 h at RT. The solvent was removed under reduced pressure. The residue was chromatographed on silica gel eluting with ethyl acetate/n-heptane (2/1).

Aufarbeitung

  1. customThe solvent was removed under reduced pressure
  2. customThe residue was chromatographed on silica gel eluting with ethyl acetate/n-heptane (2/1)

Quellen und Nachweise

ORD-Eintrag
ord-ce05e827eba5407eb510b477ae4de1d5
Quelldatensatz
uspto-grants-2005_10
Patentnummer
US06953857B2

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