HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-{5-[4-(Trifluoromethyl)phenyl]thien-3-yl}ethanol → 1-{3-Methyl-5-[4-(trifluoromethyl)phenyl]thien-2-yl}ethanol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-{5-[4-(Trifluoromethyl)phenyl]thien-3-yl}ethanol | HCID 21986431 | — |
| Edukt | 3-Methyl-5-[4-(trifluoromethyl)phenyl]thiophene-2-carbaldehyde | HCID 21986550 | — |
| Edukt | HCID 178418573 | HCID 178418573 | — |
| Produkt | 1-{3-Methyl-5-[4-(trifluoromethyl)phenyl]thien-2-yl}ethanol | HCID 21986359 | — |
Reaktionsschritte
The title compound was prepared using a method analogous to that used for the preparation of 1-{5-[4-(trifluoromethyl)phenyl]thien-3-yl}ethanol (intermediate 126) using 3-methyl-5-[4-(trifluoromethyl)phenyl]thiophene-2-carbaldehyde (intermediate 74) and methyl magnesium bromide.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07091237B2 |
| Quelldatensatz | uspto-grants-2006_08 |
| ORD ID | ord-11e7000f7bdf4162a75e44daa17cdd60 |
| Quellennotiz | uspto-grants-2006_08 |