HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HCID 10910823, Verbindung → Spermine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | HCID 10910823 | HCID 10910823 | — |
| Edukt | TriBoc-Spermine | HCID 22610912 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Produkt | Spermine | HCID 1103 | — |
Reaktionsschritte
Monoquaternary spermine containing hydrophilic head-group was prepared in a similar way to compound 3. Briefly, TriBoc-Spermine was reacted with excess of 1-azido-3-iodo-propane in the presence of excess TBA. The resulting quaternarized derivative was hydrogenised under (Pd—C) and Boc protecting group were removed using gaseous HCl in dry methanol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06958325B2 |
| Quelldatensatz | uspto-grants-2005_10 |
| ORD ID | ord-7efc57ded6f7404794f1c0a62996d328 |
| Quellennotiz | uspto-grants-2005_10 |