2-Amino-1-butanol, (-)- → HCID 178456048, Verbindung
Reaktionsgleichung
Br[C:2]1[N:10]=[C:9]([S:11][CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([F:19])[C:14]=2[F:20])[N:8]=[C:7]2[C:3]=1[N:4]=[C:5]([NH:21]C(=O)OCC)[NH:6]2.[NH2:27][C@H:28]([CH2:31][CH3:32])[CH2:29][OH:30]>>[NH2:21][C:5]1[NH:6][C:7]2[C:3]([N:4]=1)=[C:2]([NH:27][C@H:28]([CH2:31][CH3:32])[CH2:29][OH:30])[N:10]=[C:9]([S:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([F:19])[C:14]=1[F:20])[N:8]=2Komponenten
3
Versuchsvorschrift
The titled compound was prepared from the product of Example 5, step (e) (50 mg) and (2R)-2-amino-1-butanol (66 μl) using the method of example 5, step (f) and purified by preparative HPLC to yield a white solid.
Aufarbeitung
- custompurified by preparative HPLC
- customto yield a white solid
Quellen und Nachweise
- ORD-Eintrag