Ethyl 2-(4-hydroxy-2-methylphenoxy)-2-methylpropanoate → Ethyl 2-methyl-2-[2-methyl-4-(phenyl{5-[4-(trifluoromethyl)phenyl]thien-3-yl}methoxy)phenoxy]propanoate

HRID 9699Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 9699
C(OC(=O)COC1C=CC(SCC2C=C(C3C=CC(C(F)(F)F)=CC=3)OC=2)=CC=1C)C.[OH:32][C:33]1[CH:47]=[CH:46][C:36]([O:37][C:38]([CH3:45])([CH3:44])[C:39]([O:41][CH2:42][CH3:43])=[O:40])=[C:35]([CH3:48])[CH:34]=1.[C:49]1([CH:55]([C:57]2[CH:61]=[C:60]([C:62]3[CH:67]=[CH:66][C:65]([C:68]([F:71])([F:70])[F:69])=[CH:64][CH:63]=3)[S:59][CH:58]=2)O)[CH:54]=[CH:53][CH:52]=[CH:51][CH:50]=1>>[CH3:44][C:38]([O:37][C:36]1[CH:46]=[CH:47][C:33]([O:32][CH:55]([C:49]2[CH:54]=[CH:53][CH:52]=[CH:51][CH:50]=2)[C:57]2[CH:61]=[C:60]([C:62]3[CH:63]=[CH:64][C:65]([C:68]([F:69])([F:70])[F:71])=[CH:66][CH:67]=3)[S:59][CH:58]=2)=[CH:34][C:35]=1[CH3:48])([CH3:45])[C:39]([O:41][CH2:42][CH3:43])=[O:40]

Komponenten

4

Edukt 3

HCID 16756990Ethyl 2-(4-hydroxy-2-methylphenoxy)-2-methylpropanoate2×HCID 21986317Phenyl{5-[4-(trifluoromethyl)phenyl]thien-3-yl}methanol2×HCID 21986477Ethyl{2-methyl-4-[({5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetate

Produkt 1

HCID 21986485Ethyl 2-methyl-2-[2-methyl-4-(phenyl{5-[4-(trifluoromethyl)phenyl]thien-3-yl}methoxy)phenoxy]propanoate

Versuchsvorschrift

The title compound was prepared by a method analogous to that used for the preparation of ethyl{2-methyl-4-[({5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetate (example 1) using ethyl 2-(4-hydroxy-2-methylphenoxy)-2-methylpropanoate (intermediate 10) and phenyl{5-[4-(trifluoromethyl)phenyl]thien-3-yl}methanol (intermediate 127).

Quellen und Nachweise

ORD-Eintrag
ord-6f988cea8bdb463dbc69ed0a7151a8a4
Quelldatensatz
uspto-grants-2006_08
Patentnummer
US07091237B2

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