HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl formate → 2-Hydroxymethylene-17beta-hydroxy-4-methylandrost-4-en-3-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl formate | HCID 7865 | — |
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | 4-Methyltestosterone | HCID 236536 | — |
| Edukt | 4,17alpha-Dimethyl-2-hydroxymethylene Testosterone | HCID 57349609 | — |
| Produkt | 2-Hydroxymethylene-17beta-hydroxy-4-methylandrost-4-en-3-one | HCID 70603288 | — |
Reaktionsschritte
2-Hydroxymethylene-17β-hydroxy-4-methylandrost-4-en-3-one was prepared from 32.28 g. of 17β-hydroxy-4-methylandrost-4-en-3-one and 32 ml. of methyl formate by a procedure analogous to that of Example 1, part (c) except that sodium hydride (15 g., 50%) was used in place of sodium methoxide. The 20 g. of product obtained was used directly in the next reaction.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04160027 |
| Quelldatensatz | uspto-grants-1979_07 |
| ORD ID | ord-8c4c7750dc934c27b5fb5795da79a057 |
| Quellennotiz | uspto-grants-1979_07 |