Zurück
HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 971434Erstellt: 24. Oktober 2026

Methyl formate → 2-Hydroxymethylene-17beta-hydroxy-4-methylandrost-4-en-3-one

https://huagongshe.com/de/reaction/971434

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktMethyl formateHCID 7865—
EduktSodium hydrideHCID 24758—
Edukt4-MethyltestosteroneHCID 236536—
Edukt4,17alpha-Dimethyl-2-hydroxymethylene TestosteroneHCID 57349609—
Produkt2-Hydroxymethylene-17beta-hydroxy-4-methylandrost-4-en-3-oneHCID 70603288—

Reaktionsschritte

2-Hydroxymethylene-17β-hydroxy-4-methylandrost-4-en-3-one was prepared from 32.28 g. of 17β-hydroxy-4-methylandrost-4-en-3-one and 32 ml. of methyl formate by a procedure analogous to that of Example 1, part (c) except that sodium hydride (15 g., 50%) was used in place of sodium methoxide. The 20 g. of product obtained was used directly in the next reaction.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04160027
Quelldatensatzuspto-grants-1979_07
ORD IDord-8c4c7750dc934c27b5fb5795da79a057
Quellennotizuspto-grants-1979_07