HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium hydride → 1-(2-Methylbenzoyl)-3-[2-(2-cyclohexylmethylpiperidino)ethyl]-5-methoxy-2-methylindole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | 2-Methylbenzoyl chloride | HCID 70276 | — |
| Edukt | Sodium | HCID 5360545 | — |
| Edukt | 3-[2-(2-Cyclohexylmethylpiperidino)ethyl]-5-methoxy-2-methylindole | HCID 21313365 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 1-(2-Methylbenzoyl)-3-[2-(2-cyclohexylmethylpiperidino)ethyl]-5-methoxy-2-methylindole | HCID 21313328 | — |
Reaktionsschritte
1-(2-Methylbenzoyl)-3-[2-(2-cyclohexylmethylpiperidino)ethyl]-5-methoxy-2-methylindole is prepared by reaction of 3-[2-(2-cyclohexylmethylpiperidino)ethyl]-5-methoxy-2-methylindole with sodium hydride in DMF and reaction of the resulting sodium salt with 2-methylbenzoyl chloride following the procedure described above in Example 1.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04160862 |
| Quelldatensatz | uspto-grants-1979_07 |
| ORD ID | ord-c41694ae1a7b4f13a805424ba43de2c6 |
| Quellennotiz | uspto-grants-1979_07 |