Hydrogen Bromide → HCID 21312053, Verbindung

HRID 971847Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 971847
[BrH:1].O[CH2:3][CH2:4][NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([Cl:12])[CH:7]=1>>[ClH:12].[Br:1][CH2:3][CH2:4][NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([Cl:12])[CH:7]=1

Komponenten

3

Edukt 2

HCID 260Hydrogen BromideHCID 12296176N-(2-hydroxyethyl)-3-chloroaniline

Produkt 1

HCID 21312053HCID 21312053, VerbindungAusbeute 146,7 %

Reaktionsbedingungen

Temperatur
124 °C

Versuchsvorschrift

50 gm of 50% hydrobromic acid were slowly added dropwise to 19 gm of the product obtained in step (a), while stirring. The vessel containing the resulting mixture was then connected to a Vigreux-column, and the mixture was heated until a temperature of about 124° C. was reached. After three hours of heating at that temperature, about 35 ml of liquid were distilled off. The residue solidified upon cooling and was purified by washing with acetone, yielding 22 gm of the desired product which had a melting point of 148° C.

Aufarbeitung

  1. additionThe vessel containing the resulting mixture
  2. distillationwere distilled off
  3. temperatureupon cooling
  4. customwas purified
  5. washby washing with acetone

Quellen und Nachweise

ORD-Eintrag
ord-83b0134809ae452fa16118b493989fcc
Quelldatensatz
uspto-grants-1979_07
Patentnummer
US04161528

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