2-(Ethylamino)acetaldehyde → 2-[1-Ethyl-3-(5-pentyl-1,3,4-thiadiazol-2-yl)ureido]acetaldehyde
Reaktionsgleichung
[CH2:1]([C:6]1[S:10][C:9]([N:11]=[C:12]=[O:13])=[N:8][N:7]=1)[CH2:2][CH2:3][CH2:4][CH3:5].[CH2:14]([NH:16][CH2:17][CH:18]=[O:19])[CH3:15]>C1C=CC=CC=1>[CH2:14]([N:16]([CH2:17][CH:18]=[O:19])[C:12]([NH:11][C:9]1[S:10][C:6]([CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])=[N:7][N:8]=1)=[O:13])[CH3:15]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A mixture of 5-pentyl-1,3,4-thiadiazol-2-yl isocyanate dimer (0.05 mole), the dimethyl acetal of 2-ethylaminoacetaldehyde (0.1 mole) and benzene (60 ml) are charged into a glass reaction vessel equipped with a mechanical stirrer and reflux condenser. The reaction mixture is heated at reflux for a period of about 15 minutes. After this time the mixture is stripped of benzene under reduced pressure to yield a solid product as the residue. The residue is then recrystallized to yield the desired product the dimethyl acetal of 2-[1-ethyl-3-(5-pentyl-1,3,4-thiadiazol-2-yl)ureido] acetaldehyde.