Thionyl Chloride → Methyl 7-phthalimido-3-methylenecepham-4-carboxylate 1-oxide

HRID 972226Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 972226
[CH3:1][C:2](=[CH2:27])[CH:3]([N:8]1[C:11](=[O:12])[CH:10]([N:13]2[C:17](=[O:18])[C:16]3=[CH:19][CH:20]=[CH:21][CH:22]=[C:15]3[C:14]2=[O:23])[CH:9]1[S:24]([OH:26])=O)[C:4]([O:6][CH3:7])=[O:5].S(Cl)(Cl)=O>>[C:17]1(=[O:18])[N:13]([CH:10]2[C:11](=[O:12])[N:8]3[CH:3]([C:4]([O:6][CH3:7])=[O:5])[C:2](=[CH2:1])[CH2:27][S:24](=[O:26])[C@H:9]23)[C:14](=[O:23])[C:15]2=[CH:22][CH:21]=[CH:20][CH:19]=[C:16]12

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 21314440Methyl 3-methyl-2-(2-sulfino-4-oxo-3-phthalimido-1-azetidinyl)-3-butenoate

Produkt 1

HCID 69799987Methyl 7-phthalimido-3-methylenecepham-4-carboxylate 1-oxide

Versuchsvorschrift

The same procedure was followed as that described in Example 1 (J) above except 0.20 g. of methyl 3-methyl-2-(2-sulfino-4-oxo-3-phthalimido-1-azetidinyl)-3-butenoate was employed as the starting material instead of the sulfinyl chloride. The procedure provided 0.03 g. of the title compound.

Aufarbeitung

  1. customThe procedure provided 0.03 g

Quellen und Nachweise

ORD-Eintrag
ord-b2c8bdd15e0c44e99e1cc50272da92c6
Quelldatensatz
uspto-grants-1977_10
Patentnummer
US04052387

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