Cortisol → HCID 178441396, Verbindung

HRID 973881Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 973881
[CH3:1][CH2:2][CH2:3][CH2:4][CH:5]1[C:40](=[O:41])[O:39][CH:38]([CH:42]([CH:44]([OH:52])[CH2:45][CH2:46][CH2:47][NH:48][C:49]([NH2:51])=[NH:50])[CH3:43])[CH:37]([CH3:53])[CH:36]=[C:35]([CH3:54])[CH2:34][CH2:33][CH2:32][CH2:31][CH:30]([OH:55])[CH2:29][CH:28]([OH:56])[CH2:27][CH:26]([OH:57])[CH2:25][CH:24]([OH:58])[CH2:23][CH:22]([OH:59])[CH:21]([O:60][C@H:61]2[O:65][C@H:64]([CH2:66][OH:67])[C@@H:63]([OH:68])[C@@H:62]2[OH:69])[CH:20]=[C:19]([CH3:70])[CH:18]([OH:71])[CH2:17][CH2:16][CH2:15][CH:14]([OH:72])[CH2:13][CH2:12][CH2:11][CH:10]([OH:73])[CH2:9][CH2:8][CH:7]([CH3:74])[CH:6]1[OH:75].[CH3:76][C@@H:77]1[C@@H:116]([OH:117])[C@@H:115]([CH3:118])[C@H:114]([CH3:119])[O:113][C:111](=[O:112])[CH2:110][C@H:109]([OH:120])[CH2:108][C@H:107]([OH:121])[CH2:106][C@H:105]([OH:122])[CH2:104][CH2:103][C@@H:102]([OH:123])[C@H:101]([OH:124])[CH2:100][C@@:98]2([OH:125])[O:99][C@H:94]([C@H:95]([C:127]([OH:129])=[O:128])[C@@H:96]([OH:126])[CH2:97]2)[CH2:93][C@@H:92]([O:130][C@H:131]2[O:136][C@@H:135]([CH3:137])[C@H:134]([OH:138])[C@@H:133]([NH2:139])[C@H:132]2[OH:140])[CH:91]=[CH:90][CH:89]=[CH:88][CH:87]=[CH:86][CH:85]=[CH:84][CH2:83][CH2:82][CH:81]=[CH:80][CH:79]=[CH:78]1.[CH3:141][C@@:142]12[C@H:152]3[C@@H:153]([OH:166])[CH2:154][C@:155]4([CH3:165])[C@@:159]([OH:164])([C:160]([CH2:162][OH:163])=[O:161])[CH2:158][CH2:157][C@H:156]4[C@@H:151]3[CH2:150][CH2:149][C:148]1=[CH:147][C:145](=[O:146])[CH2:144][CH2:143]2>>[CH3:1][CH2:2][CH2:3][CH2:4][CH:5]1[C:40](=[O:41])[O:39][CH:38]([CH:42]([CH:44]([OH:52])[CH2:45][CH2:46][CH2:47][NH:48][C:49]([NH2:51])=[NH:50])[CH3:43])[CH:37]([CH3:53])[CH:36]=[C:35]([CH3:54])[CH2:34][CH2:33][CH2:32][CH2:31][CH:30]([OH:55])[CH2:29][CH:28]([OH:56])[CH2:27][CH:26]([OH:57])[CH2:25][CH:24]([OH:58])[CH2:23][CH:22]([OH:59])[CH:21]([O:60][C@H:61]2[O:65][C@H:64]([CH2:66][OH:67])[C@@H:63]([OH:68])[C@@H:62]2[OH:69])[CH:20]=[C:19]([CH3:70])[CH:18]([OH:71])[CH2:17][CH2:16][CH2:15][CH:14]([OH:72])[CH2:13][CH2:12][CH2:11][CH:10]([OH:73])[CH2:9][CH2:8][CH:7]([CH3:74])[CH:6]1[OH:75].[CH3:141][C@@:142]12[C@H:152]3[C@@H:153]([OH:166])[CH2:154][C@:155]4([CH3:165])[C@@:159]([OH:164])([C:160]([CH2:162][OH:163])=[O:161])[CH2:158][CH2:157][C@H:156]4[C@@H:151]3[CH2:150][CH2:149][C:148]1=[CH:147][C:145](=[O:146])[CH2:144][CH2:143]2.[CH3:76][C@@H:77]1[C@@H:116]([OH:117])[C@@H:115]([CH3:118])[C@H:114]([CH3:119])[O:113][C:111](=[O:112])[CH2:110][C@H:109]([OH:120])[CH2:108][C@H:107]([OH:121])[CH2:106][C@H:105]([OH:122])[CH2:104][CH2:103][C@@H:102]([OH:123])[C@H:101]([OH:124])[CH2:100][C@@:98]2([OH:125])[O:99][C@H:94]([C@H:95]([C:127]([OH:129])=[O:128])[C@@H:96]([OH:126])[CH2:97]2)[CH2:93][C@@H:92]([O:130][C@H:131]2[O:136][C@@H:135]([CH3:137])[C@H:134]([OH:138])[C@@H:133]([NH2:139])[C@H:132]2[OH:140])[CH:91]=[CH:90][CH:89]=[CH:88][CH:87]=[CH:86][CH:85]=[CH:84][CH2:83][CH2:82][CH:81]=[CH:80][CH:79]=[CH:78]1

Komponenten

4

Edukt 3

HCID 5754CortisolHCID 44424838NystatinHCID 178441392HCID 178441392, Verbindung

Produkt 1

HCID 178441396HCID 178441396, Verbindung

Versuchsvorschrift

From 20 g of Primycin and 40.0 g of N-methyl-pyrrolidone-2 a gel is prepared at 70° C., whereupon nystatin and hydrocortisone are added at room temperature under constant stirring. A very viscous solution is obtained which becomes gelous on standing for 24 hours.

Aufarbeitung

  1. additionare added at room temperature under constant stirring
  2. customA very viscous solution is obtained which

Quellen und Nachweise

ORD-Eintrag
ord-b01e97983ae342f2a6a3246acefdddf6
Quelldatensatz
uspto-grants-1991_11
Patentnummer
US05064815

Notizen zur Reaktion

Wird geladen…