3-Chloropropionitrile → HCID 178511037, Verbindung

HRID 974428Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 974428
[S:1]([NH2:5])([NH2:4])(=[O:3])=[O:2].Cl[C:7]1[CH:12]=[C:11]([Cl:13])[CH:10]=[C:9]([Cl:14])[C:8]=1[S:15]([OH:18])(=[O:17])=[O:16].[Cl:19][CH2:20][CH2:21][C:22]#[N:23]>C(Cl)Cl.CC(C)=O>[Cl:14][C:9]1[CH:10]=[C:11]([Cl:13])[C:12]([Cl:19])=[CH:7][C:8]=1[S:15]([OH:18])(=[O:17])=[O:16].[S:1]([NH:5][C:22](=[NH:23])[CH2:21][CH2:20][Cl:19])(=[O:3])(=[O:2])[NH2:4]

Komponenten

6

Edukt 3

HCID 109633-ChloropropionitrileHCID 82267SulfamideHCID 1286712,4,6-Trichlorobenzenesulfonate

Produkt 1

HCID 178511037HCID 178511037, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 180AcetoneLösungsmittelHCID 6344DichloromethaneLösungsmittel

Reaktionsbedingungen

Temperatur
57.5 °C

Versuchsvorschrift

Sulfamide (9.6 g, 0.1 mole) was added to a solution of 2,4,6-trichlorobenzenesulfonic acid (52.2 g, 0.2 mole) in 3-chloropropionitrile (51.3 g, 0.6 mole). The suspension was heated at 55-60° C., for 18 hours. At the end of the heating period, the mixture was cooled to room temperature, diluted with methylene chloride (150 ml), and filtered. The solid, thus obtained, was suspended in acetone (50 ml) and the suspension filtered and the product dried.

Aufarbeitung

  1. temperatureAt the end of the heating period, the mixture was cooled to room temperature
  2. filtrationfiltered
  3. customThe solid, thus obtained
  4. filtrationthe suspension filtered
  5. customthe product dried

Quellen und Nachweise

ORD-Eintrag
ord-286eded3fc4740119c3ad4ed69bbb3ea
Quelldatensatz
uspto-grants-1991_11
Patentnummer
US05068405

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