ethyl 3,3-bis(4-fluorophenyl)-2-(1-ethyl-1H-tetrazol-5-yl)-2-propenoate → 3,3-Bis(4-fluorophenyl)-2-(2-ethyl-2H-tetrazol-5-yl)-2-propenol

HRID 974468Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 974468
FC1C=CC(C(C2C=CC(F)=CC=2)=C(C2N(CC)N=NN=2)C(OCC)=O)=CC=1.[F:29][C:30]1[CH:35]=[CH:34][C:33]([C:36]([C:50]2[CH:55]=[CH:54][C:53]([F:56])=[CH:52][CH:51]=2)=[C:37]([C:43]2[N:44]=[N:45][N:46]([CH2:48][CH3:49])[N:47]=2)[C:38](OCC)=[O:39])=[CH:32][CH:31]=1>>[F:29][C:30]1[CH:35]=[CH:34][C:33]([C:36]([C:50]2[CH:51]=[CH:52][C:53]([F:56])=[CH:54][CH:55]=2)=[C:37]([C:43]2[N:44]=[N:45][N:46]([CH2:48][CH3:49])[N:47]=2)[CH2:38][OH:39])=[CH:32][CH:31]=1

Komponenten

3

Edukt 2

HCID 14723820ethyl 3,3-bis(4-fluorophenyl)-2-(1-ethyl-1H-tetrazol-5-yl)-2-propenoateHCID 14723821Ethyl 3,3-bis(4-fluorophenyl)-2-(2-ethyl-2H-tetrazol-5-yl)-2-propenoate

Produkt 1

HCID 147238243,3-Bis(4-fluorophenyl)-2-(2-ethyl-2H-tetrazol-5-yl)-2-propenolAusbeute 101,1 %

Versuchsvorschrift

The general procedure of Example 46 was repeated, except that the ethyl 3,3-bis(4-fluorophenyl)-2-(1-ethyl-1H-tetrazol-5-yl)-2-propenoate utilized therein was replaced with 1.0 g of ethyl 3,3-bis(4-fluorophenyl)-2-(2-ethyl-2H-tetrazol-5-yl)-2-propenoate and there was thereby produced 0.9 g of the title compound; M.p.=82°-84° C.

Quellen und Nachweise

ORD-Eintrag
ord-0e4d416bb6344f6a8bf9b0700b9217b2
Quelldatensatz
uspto-grants-1991_11
Patentnummer
US05068346

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