Potassium Fluoride → 2-Chloro-4,5-difluorobenzoyl fluoride

HRID 974661Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 974661
[Cl:1][C:2]1[CH:10]=[C:9]([F:11])[C:8]([F:12])=[CH:7][C:3]=1[C:4](Cl)=[O:5].[F-:13].[K+]>>[Cl:1][C:2]1[CH:10]=[C:9]([F:11])[C:8]([F:12])=[CH:7][C:3]=1[C:4]([F:13])=[O:5]

Komponenten

3

Edukt 2

HCID 522689Potassium FluorideHCID 101982172-Chloro-4,5-difluorobenzoyl chloride

Produkt 1

HCID 147961732-Chloro-4,5-difluorobenzoyl fluoride

Versuchsvorschrift

Into a 200 cc glass reactor equipped with a reflux condensor, 50 g of 2-chloro-4,5-difluorobenzoylchloride, 13.7 g of spray dried potassium fluoride and 100 g of sulforane were charged and reacted at 135° C. for 4 hours under stirring. After cooling, the inorganic salts were filtered off, and the residue was subjected to distillation under reduced pressure to obtain 42 g of 2-chloro-4,5-difluorobenzoyl fluoride. The physical properties of the obtained 2-choloro-4,5-difluorobenzoyl fluoride were as follows.

Aufarbeitung

  1. additionwere charged
  2. customreacted at 135° C. for 4 hours
  3. temperatureAfter cooling
  4. filtrationthe inorganic salts were filtered off
  5. distillationthe residue was subjected to distillation under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-735d3e84f9dd4282aa820e1826159228
Quelldatensatz
uspto-grants-1991_11
Patentnummer
US05068449

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