Hydrochloric Acid → 2-Chloro-2-methyl-3-nitrosopentane

HRID 975621

Reaktionsgleichung

Reaktionsgleichung von HRID 975621
[ClH:1].[N:2]([O:4]CCC(C)C)=O.[CH3:10][C:11](=[CH:13][CH2:14][CH3:15])[CH3:12]>>[Cl:1][C:11]([CH3:12])([CH3:10])[CH:13]([N:2]=[O:4])[CH2:14][CH3:15]

Komponenten

4

Edukt 3

HCID 313Hydrochloric AcidHCID 8053Isoamyl NitriteHCID 122432-Methyl-2-pentene

Produkt 1

HCID 122253792-Chloro-2-methyl-3-nitrosopentane

Reaktionsbedingungen

Temperatur
5 °C

Versuchsvorschrift

Concentrated HCl (9.0 mL, 0.11 mol) was added to a cooled (0°-5° C.) solution of isoamyl nitrite (14.8 g, 0.1 mol) and 2-methyl-2-pentene (8.4 g, 0.1 mol). The temperature was maintained below 5° C. during the addition and the reaction mixture was stirred at 5° C. for an additional 30 min. The product was filtered and washed with a cold (-20° C.) 1:1 mixture of petroleum ether. The solid was further washed with petroleum ether to afford a white solid. Yield: 4.9 g (34%); mp 85°-86° C. 1H NMR CDCl3) δ0.98 (CH2CH3), 1.68 (d, 6H, CH3), 2.05 (m, 2H, CH2CH3), 5.88 (dd, 1H, CHNO). MS: 299 (2M+H)+.

Aufarbeitung

  1. temperatureThe temperature was maintained below 5° C. during the addition
  2. filtrationThe product was filtered
  3. washwashed with a cold (-20° C.) 1:1 mixture of petroleum ether
  4. washThe solid was further washed with petroleum ether
  5. customto afford a white solid

Quellen und Nachweise

ORD-Eintrag
ord-09c2b6275bc446c5ab4d3915ee95a7c6
Quelldatensatz
uspto-grants-1997_03
Patentnummer
US05608110

Verknüpfte Notizen

Wird geladen…