Acetate → HCID 131719940, Verbindung

HRID 977220

Reaktionsgleichung

Reaktionsgleichung von HRID 977220
C(OC([NH:8][CH2:9][C:10]1[CH:15]=[CH:14][C:13]([N:16]2[CH2:20][CH:19]([C:21]([N:23]3[CH2:28][CH2:27][N:26]([CH2:29][CH2:30][C:31]([OH:33])=[O:32])[CH2:25][CH2:24]3)=[O:22])[O:18][C:17]2=[O:34])=[CH:12][CH:11]=1)=O)(C)(C)C.C([O-])(=O)C.[ClH:39]>>[ClH:39].[ClH:39].[NH2:8][CH2:9][C:10]1[CH:15]=[CH:14][C:13]([N:16]2[CH2:20][CH:19]([C:21]([N:23]3[CH2:24][CH2:25][N:26]([CH2:29][CH2:30][C:31]([OH:33])=[O:32])[CH2:27][CH2:28]3)=[O:22])[O:18][C:17]2=[O:34])=[CH:12][CH:11]=1

Komponenten

4

Edukt 3

HCID 175AcetateHCID 313Hydrochloric AcidHCID 199654883-{1-[3-(4-Tert-butoxycarbonylaminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperazinyl}propionic acid

Produkt 1

HCID 131719940HCID 131719940, Verbindung

Versuchsvorschrift

0.43 g of 3-{1-[3-(4-tert-butoxycarbonylaminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperazinyl}propionic acid, acetate, is stirred in 30 ml of ethereal HCl solution at room temperature. The precipitate formed is filtered off with suction, washed with a little ether and dried. 3-{1-[3-(4-aminomethylphenyl)-2-oxo-5-oxazolidinylcarbonyl]-4-piperazinyl}propionic acid, dihydrochloride, is obtained, m.p. 184°-186°.

Aufarbeitung

  1. customThe precipitate formed
  2. filtrationis filtered off with suction
  3. washwashed with a little ether
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-d90db408527948a6b84d131e63b4a8f9
Quelldatensatz
uspto-grants-1997_03
Patentnummer
US05614535

Verknüpfte Notizen

Wird geladen…