Hydrochloric Acid → 2,4-Piperidinedione, 1-(2-phenylethyl)-
Reaktionsgleichung
[CH2:1]([N:9]1[CH2:14][CH2:13][C:12](=[O:15])[CH:11](C(=O)C)[C:10]1=[O:19])[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.Cl>C(O)C>[CH2:1]([N:9]1[CH2:14][CH2:13][C:12](=[O:15])[CH2:11][C:10]1=[O:19])[CH2:2][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
1-Phenethyl-3-acetyl-2,4-dioxopiperidine (5.0 g) and 10% hydrochloric acid (30 ml) are added to ethanol (50 ml), and the mixture is refluxed for 6 hours. After distilling off the solvent, the residue is dissolved in chloroform, and the solution is washed with a saturated sodium chloride solution, dried and then distilled to remove the solvent to give 1-phenethyl-2,4-dioxopiperidine (3.62 g, 86.4%) as an oily substance.