Deferoxamine → HCID 131715138, Verbindung

HRID 979002

Reaktionsgleichung

Reaktionsgleichung von HRID 979002
[CH2:1]=[CH:2][CH:3]=[O:4].[CH3:5][C:6]([N:8]([OH:43])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][NH:14][C:15]([CH2:17][CH2:18][C:19]([N:21]([OH:42])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][NH:27][C:28]([CH2:30][CH2:31][C:32]([N:34]([OH:41])[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][NH2:40])=[O:33])=[O:29])=[O:20])=[O:16])=[O:7]>CS(C)=O>[CH2:1]=[CH:2][CH:3]=[O:4].[CH3:5][C:6]([N:8]([OH:43])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][NH:14][C:15]([CH2:17][CH2:18][C:19]([N:21]([OH:42])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][NH:27][C:28]([CH2:30][CH2:31][C:32]([N:34]([OH:41])[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][NH2:40])=[O:33])=[O:29])=[O:20])=[O:16])=[O:7]

Komponenten

4

Edukt 2

HCID 2973DeferoxamineHCID 7847Acrolein

Produkt 1

HCID 131715138HCID 131715138, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 679Dimethyl SulfoxideLösungsmittel2×

Versuchsvorschrift

To a solution of polyacrolein (125 mg) in dimethylsulfoxide (2.5 ml), a solution of deferoxamine (105 mg) in dimethylsulfoxide (2.5 ml) was added, and the resultant mixture was agitated at room temperature for 3 hours to produce a solution containing the polyacrolein-deferixamine condensation product, which is useful as a non-radioactive carrier.

Aufarbeitung

  1. customto produce a solution
  2. additioncontaining

Quellen und Nachweise

ORD-Eintrag
ord-512ffb435e5b4d9ab56cd3ade5c5004c
Quelldatensatz
uspto-grants-1987_05
Patentnummer
US04666697

Verknüpfte Notizen

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