HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dimethylacetamide → Quinoline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dimethylacetamide | HCID 31374 | — |
| Edukt | 4,5-Difluorophthalic Anhydride | HCID 639745 | — |
| Edukt | 4,5-Difluorophthalic Acid | HCID 643382 | — |
| Lösungsmittel | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Produkt | Quinoline | HCID 7047 | — |
| Produkt | 3,4-Difluorobenzoic acid | HCID 99166 | — |
Reaktionsschritte
Surprisingly, we have found that 4,5-difluorophthalic anhydride and 4,5-difluorophthalic acid may be selectively decarboxylated in N-methyl-pyrrolidone, dimethyl acetamide or quinoline to yield 3,4-difluorobenzoic acid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04994606 |
| Quelldatensatz | uspto-grants-1991_02 |
| ORD ID | ord-d666b3202b4042d58b36b042b1da0a9d |
| Quellennotiz | uspto-grants-1991_02 |