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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 982813Erstellt: 23. Oktober 2026

1-Methylpiperazine → 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-[3-(4-methyl-1-piperazinyl)propyl]-2H-pyridazin-3-one

https://huagongshe.com/de/reaction/982813

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-MethylpiperazineHCID 53167—
Edukt2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-(3-metha nesulfonyloxypropyl)-2H-pyridazin-3-oneHCID 21991559—
Produkt2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-[3-(4-methyl-1-piperazinyl)propyl]-2H-pyridazin-3-oneHCID 1013653662%

Reaktionsschritte

Following the procedure of Example 1(10), 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-(3-methanesulfonyloxypropyl)-2H-pyridazin-3-one and 1-methylpiperazine were reacted to yield the title compound as a yellow oil (yield: 62.0%).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06861428B2
Quelldatensatzuspto-grants-2005_03
ORD IDord-368e5c7e5ef845389a29af90a5fb975c
Quellennotizuspto-grants-2005_03