HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Diethanolamine → 4-[3-[N,N-bis(2-hydroxyethyl)amino]propyl]-2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Diethanolamine | HCID 8113 | — |
| Edukt | 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-(3-metha nesulfonyloxypropyl)-2H-pyridazin-3-one | HCID 21991559 | — |
| Produkt | 4-[3-[N,N-bis(2-hydroxyethyl)amino]propyl]-2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one | HCID 21991397 | 13,1% |
Reaktionsschritte
Following the procedure of Example 1(10), 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-(3-methanesulfonyloxypropyl)-2H-pyridazin-3-one and diethanolamine were reacted to yield the title compound as a yellow oil (yield: 13.1%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06861428B2 |
| Quelldatensatz | uspto-grants-2005_03 |
| ORD ID | ord-a8e7b89f91004496a4d9ba1ec2b74b07 |
| Quellennotiz | uspto-grants-2005_03 |