Benzene → 3,5,5-Trimethylhexanoylbenzene

HRID 983741

Reaktionsgleichung

Reaktionsgleichung von HRID 983741
[Cl-].[Al+3].[Cl-].[Cl-].[CH3:5][CH:6]([CH2:11][C:12]([CH3:15])([CH3:14])[CH3:13])[CH2:7][C:8](Cl)=[O:9].[CH:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH3:5][CH:6]([CH2:11][C:12]([CH3:15])([CH3:14])[CH3:13])[CH2:7][C:8]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[O:9]

Komponenten

4

Edukt 3

HCID 241BenzeneHCID 1619293,5,5-Trimethylhexanoyl chlorideHCID 6451240Aluminum(III) Chloride

Produkt 1

HCID 222694783,5,5-Trimethylhexanoylbenzene

Versuchsvorschrift

To a mixture of 143.3 grams of aluminum chloride and 400 mL of benzene was added 100 grams of 3,5,5-trimethylhexanoyl chloride over a 50 minute period at a rate such that the temperature did not exceed 35° C. When the addition was complete, the mixture was stirred at room temperature for three hours. The mixture was poured over 500 grams of ice and extracted with 400 mL of ethyl acetate. The organic phase was washed with brine, dried over magnesium sulfate, filtered and the solvent was removed in vacuo to give 3,5,5-trimethylhexanoylbenzene.

Aufarbeitung

  1. customdid not exceed 35° C
  2. additionWhen the addition
  3. extractionextracted with 400 mL of ethyl acetate
  4. washThe organic phase was washed with brine
  5. dry with materialdried over magnesium sulfate
  6. filtrationfiltered
  7. customthe solvent was removed in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-7b4b6970e38e48e3a6b6c40f9c13e7c2
Quelldatensatz
uspto-grants-2005_03
Patentnummer
US06864396B2

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