HCID 22557787, Verbindung → HCID 22558017, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[C:7]([O:8][CH3:9])=[CH:6][C:5]([C:10]2[CH:15]=[C:14]([CH2:16][N:17]3[CH2:22][CH2:21][CH:20]([NH:23][CH3:24])[CH2:19][CH2:18]3)[CH:13]=[CH:12][N:11]=2)=[CH:4][C:3]=1[O:25][CH3:26].[Cl:27][C:28]1[C:33]([O:34][CH3:35])=[CH:32][C:31]([C:36]2[CH:41]=[C:40]([CH2:42]Cl)[CH:39]=[CH:38][N:37]=2)=[CH:30][C:29]=1[O:44][CH3:45]>>[ClH:1].[ClH:27].[ClH:1].[ClH:1].[Cl:1][C:2]1[C:7]([O:8][CH3:9])=[CH:6][C:5]([C:10]2[CH:15]=[C:14]([CH2:16][N:17]3[CH2:18][CH2:19][CH:20]([N:23]([CH2:42][C:40]4[CH:39]=[CH:38][N:37]=[C:36]([C:31]5[CH:32]=[C:33]([O:34][CH3:35])[C:28]([Cl:27])=[C:29]([O:44][CH3:45])[CH:30]=5)[CH:41]=4)[CH3:24])[CH2:21][CH2:22]3)[CH:13]=[CH:12][N:11]=2)=[CH:4][C:3]=1[O:25][CH3:26]Komponenten
3
Versuchsvorschrift
1-[[2-(4-chloro-3,5-dimethoxyphenyl)pyridin-4-yl]methyl]-4-methylaminopiperidine (195 mg) and 2-(4-chloro-3,5-dimethoxyphenyl)-4-chloromethylpyridine (152 mg) were condensed in the same manner as described in Example 2. A free base obtained was converted to a tetrahydrochloride giving yellow powder.
Aufarbeitung
- customcondensed in the same manner
- customA free base obtained