3-Methoxyaniline → Tert-butyl 4-(3-methoxyanilino)piperidine-1-carboxylate

Reaktionsgleichung

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][C:11](=O)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH3:15][O:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([NH2:23])[CH:18]=1>>[CH3:15][O:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([NH:23][CH:11]2[CH2:12][CH2:13][N:8]([C:6]([O:5][C:1]([CH3:4])([CH3:3])[CH3:2])=[O:7])[CH2:9][CH2:10]2)[CH:18]=1

Komponenten

Edukt 2

HCID 108243-Methoxyaniline

HCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Produkt 1

HCID 22557965Tert-butyl 4-(3-methoxyanilino)piperidine-1-carboxylate

Versuchsvorschrift

1-(tert-Butoxycarbonyl)-4-piperidone (4.78 g) and m-anisidine (2.96 g) were condensed in the same manner as described in Preparation Example 37 to give the title compound.

Aufarbeitung

customcondensed in the same manner
customas described in Preparation Example 37

Quellen und Nachweise

ORD-Eintrag: ord-f20dfa4df1d04aa795351d55cd3ddff7
Quelldatensatz: uspto-grants-2005_03
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US06867221B2

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