4-Chloroaniline → Tert-butyl 4-(4-chlorophenylamino)piperidine-1-carboxylate

HRID 984281

Reaktionsgleichung

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][C:11](=O)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[Cl:15][C:16]1[CH:22]=[CH:21][C:19]([NH2:20])=[CH:18][CH:17]=1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]([NH:20][C:19]2[CH:21]=[CH:22][C:16]([Cl:15])=[CH:17][CH:18]=2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Komponenten

Edukt 2

HCID 78124-Chloroaniline

HCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Produkt 1

HCID 1491503Tert-butyl 4-(4-chlorophenylamino)piperidine-1-carboxylate

Versuchsvorschrift

1-(tert-Butoxycarbonyl)-4-piperidone (5.00 g) and 4-chloroaniline (3.05 g) was treated in the same manner as described in Preparation Example 37 to give white powder of the title compound.

Aufarbeitung

customas described in Preparation Example 37

Quellen und Nachweise

ORD-Eintrag: ord-f94b60ea74bb454684dced03a68c0298
Quelldatensatz: uspto-grants-2005_03
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US06867221B2

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