HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridine → 1-(tert-butoxycarbonyl)-4-[N-(3,4-difluorophenyl)-N-[[2-(3,4,5-trimethoxyphenyl) pyridin-4-yl]methyl]amino]piperidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridine | HCID 12019237 | — |
| Edukt | 1-Boc-4-[(3,4-difluorophenyl)amino]-piperidine | HCID 22558033 | — |
| Produkt | 1-(tert-butoxycarbonyl)-4-[N-(3,4-difluorophenyl)-N-[[2-(3,4,5-trimethoxyphenyl) pyridin-4-yl]methyl]amino]piperidine | HCID 22558036 | — |
Reaktionsschritte
1-(tert-Butoxycarbonyl)-4-[(3,4-difluorophenyl)amino]piperidine (625 mg) and 4-chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine (588 mg) was treated in the same manner as described in Example 9 to give light yellow amorphous of the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06867221B2 |
| Quelldatensatz | uspto-grants-2005_03 |
| ORD ID | ord-b4d8153a6ece4990993b0aa4b1b1f4f6 |
| Quellennotiz | uspto-grants-2005_03 |