Diisobutylaluminum hydride → (E)-3-(2'-methyl-biphenyl-4-yl)-but-2-en-1-ol

HRID 984356Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 984356
CC(C[AlH]CC(C)C)C.[CH3:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[C:17]1[CH:22]=[CH:21][C:20](/[C:23](/[CH3:30])=[CH:24]/[C:25](OCC)=[O:26])=[CH:19][CH:18]=1>>[CH3:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[C:17]1[CH:18]=[CH:19][C:20](/[C:23](/[CH3:30])=[CH:24]/[CH2:25][OH:26])=[CH:21][CH:22]=1

Komponenten

3

Edukt 2

HCID 14487Diisobutylaluminum hydrideHCID 22557711(E)-ethyl 3-(2'-methyl-biphenyl-4-yl)-but-2-enoate

Produkt 1

HCID 22557657(E)-3-(2'-methyl-biphenyl-4-yl)-but-2-en-1-ol

Versuchsvorschrift

The colourless oil (E)-3-(2′-methyl-biphenyl-4-yl)-but-2-en-1-ol was prepared by DIBAL-H reduction of (E)-ethyl 3-(2′-methyl-biphenyl-4-yl)-but-2-enoate by a procedure analogous to that described in example 50b.

Quellen und Nachweise

ORD-Eintrag
ord-41bc202b34404362b88808e0356c3410
Quelldatensatz
uspto-grants-2005_03
Patentnummer
US06867218B2

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