HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(Bromomethyl)-1,2-difluorobenzene → 2-(3,4-difluorobenzyl)-6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(Bromomethyl)-1,2-difluorobenzene | HCID 581436 | — |
| Edukt | 6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one | HCID 21991432 | — |
| Produkt | 2-(3,4-difluorobenzyl)-6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one | HCID 21991666 | 92,1% |
Reaktionsschritte
Following the procedure of Example 1(6), 6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one and 3, 4-difluorobenzyl bromide were reacted to yield the title compound as a yellow crystalline powder (yield: 92.1%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06869954B2 |
| Quelldatensatz | uspto-grants-2005_03 |
| ORD ID | ord-8f28a16359f94ff4895d01ff1899a8cc |
| Quellennotiz | uspto-grants-2005_03 |