3-(5-Nitrofuran-2-yl)prop-2-enal → 3-(6-Methoxy-3-pyridyl)-2-propenoic acid [3-(5-nitro-2-furyl)-2-propen-1-ylidene]hydrazide

HRID 986223Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 986223
[CH3:1][O:2][C:3]1[N:8]=[CH:7][C:6]([CH:9]=[CH:10][C:11]([NH:13][NH2:14])=[O:12])=[CH:5][CH:4]=1.[N+:15]([C:18]1[O:22][C:21]([CH:23]=[CH:24][CH:25]=O)=[CH:20][CH:19]=1)([O-:17])=[O:16]>CO>[N+:15]([C:18]1[O:22][C:21]([CH:23]=[CH:24][CH:25]=[N:14][NH:13][C:11](=[O:12])[CH:10]=[CH:9][C:6]2[CH:7]=[N:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[CH:20][CH:19]=1)([O-:17])=[O:16]

Komponenten

4

Edukt 2

HCID 158633-(5-Nitrofuran-2-yl)prop-2-enalHCID 704352203-(6-Methoxy-3-pyridyl)-2-propenoic acid hydrazide

Produkt 1

HCID 542876343-(6-Methoxy-3-pyridyl)-2-propenoic acid [3-(5-nitro-2-furyl)-2-propen-1-ylidene]hydrazide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

To a lukewarm solution of 0.85 g (4.4. mmol) of 3-(6-methoxy-3-pyridyl)-2-propenoic acid hydrazide in 50 ml of methanol, 0.75 g (4.5 mmol) of 3-(5-nitro-2-furyl)-2-propenal is added. A solid crystallizes slowly in the resulting homogenous solution. After the mixture has been stirred for several hours, these crystals are drained, washed with methanol and ether and dried under reduced pressure at 100° C. for 8 h.

Aufarbeitung

  1. customA solid crystallizes slowly in the resulting homogenous solution
  2. washwashed with methanol and ether
  3. customdried under reduced pressure at 100° C. for 8 h.

Quellen und Nachweise

ORD-Eintrag
ord-66680e05d6804ff5bb58b7465d38ba45
Quelldatensatz
uspto-grants-1987_12
Patentnummer
US04711892

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