HCID 86741940, Verbindung → Ethyl 3-[4-(pyridin-3-yloxy)phenyl]propionate

HRID 986432Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 986432
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([O:7][C:8]2[CH:13]=[CH:12][C:11](/[CH:14]=[CH:15]/[C:16]([O:18][CH2:19][CH3:20])=[O:17])=[CH:10][CH:9]=2)[CH:2]=1.[H][H]>C(O)C.[C].[Pd]>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([O:7][C:8]2[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])=[CH:10][CH:9]=2)[CH:2]=1

Komponenten

5

Edukt 2

HCID 86741940HCID 86741940, VerbindungHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 20148644Ethyl 3-[4-(pyridin-3-yloxy)phenyl]propionateAusbeute 99 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

In 20 ml of ethanol was dissolved 2.0 g of ethyl (E)-3-[4-(pyridin-3-yloxy)phenyl]acrylate, and to the resulting solution was added 1.0 g of 5% palladiumcarbon, after which the resulting mixture was stirred in a hydrogen atmosphere at room temperature for 5 hours. The reaction mixture was filtered and the filtrate thus obtained was concentrated under reduced pressure to obtain 2.0 g (yield 99%) of colorless, oily ethyl 3-[4-(pyridin-3-yloxy)phenyl]propionate.

Aufarbeitung

  1. filtrationThe reaction mixture was filtered
  2. customthe filtrate thus obtained
  3. concentrationwas concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-a30f77edf86449639f06788431823da9
Quelldatensatz
uspto-grants-1987_12
Patentnummer
US04713387

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