Furan-3-carbohydrazide → HCID 178527770, Verbindung
Reaktionsgleichung
[O:1]1[CH:5]=[CH:4][C:3]([C:6]([NH:8][NH2:9])=O)=[CH:2]1.Cl[C:11]1[CH:12]=[CH:13][C:14]([C:20]#[N:21])=[C:15]([N:17]=[C:18]=[S:19])[CH:16]=1>>[O:1]1[CH:5]=[CH:4][C:3]([C:6]2[N:21]=[C:20]3[N:9]([C:18]([SH:19])=[N:17][C:15]4[CH:16]=[CH:11][CH:12]=[CH:13][C:14]=43)[N:8]=2)=[CH:2]1Komponenten
3
Versuchsvorschrift
As in Example 39, 3-furoic acid hydrazide is reacted with 5-chloro-2-cyanophenyl isothiocyanate to produce 2-(3-furyl)-5-mercapto-[1,2,4]triazolo[1,5-c]quinazoline, mp>300°, which is converted to the 5-methylthio compound and thence to 9-chloro-2-(3-furyl)-5-imino-5,6-dihydro[1,2,4]triazolo[1,5-c]quinazoline, purified as the methanesulphonate salt, mp 290°-292°.
Quellen und Nachweise
- ORD-Eintrag
- ord-f9bb581aa134498392da13d6677f2341
- Quelldatensatz
- uspto-grants-1987_12
- Patentnummer
- US04713383