Methyl phenylacetate → Potassium phenylacetate

Reaktionsgleichung

[OH-].[K+:2].C1C=CC(P(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.[C:22]1([CH2:28][C:29]([O:31]C)=[O:30])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[C:22]1([CH2:28][C:29]([O-:31])=[O:30])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1.[K+:2]

Komponenten

Edukt 3

HCID 7559Methyl phenylacetate

HCID 11776Triphenylphosphine

HCID 14797Potassium Hydroxide

Produkt 1

HCID 23675783Potassium phenylacetateAusbeute 92 %

Versuchsvorschrift

Under the reaction conditions described in Example 1, 64 ml KOH and 19.2 ml PPh3 were added over 43 min. After five more minutes, the reactor was cooled and vented. A 92% yield of potassium phenylacetate and 4% methyl phenylacetate was obtained on a nearly quantitative conversion. 98% of the stiochiometric amount of KOH was added.