Tetrahydrothiophene → 1-(3,3-Dimethyl-2-oxobutyl)thiolan-1-ium bromide

HRID 988945

Reaktionsgleichung

Reaktionsgleichung von HRID 988945
[S:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[Br:6][CH2:7][C:8](=[O:13])[C:9]([CH3:12])([CH3:11])[CH3:10]>CC(C)=O>[Br-:6].[O:13]=[C:8]([C:9]([CH3:12])([CH3:11])[CH3:10])[CH2:7][S+:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1

Komponenten

4

Edukt 2

HCID 1127TetrahydrothiopheneHCID 21642Bromopinacolone

Produkt 1

HCID 225645781-(3,3-Dimethyl-2-oxobutyl)thiolan-1-ium bromideAusbeute 85 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

Using the 100-millilitter 3-port flask, 2 grams of tetrahydrothiophene was dissolved in 20 milli-litter of acetone. 4.87 grams of 1-bromo-3,3-dimethyl-2-butanone was dropped into the solution over agitation. After 24 hours, white crystal was precipitated, and was filtrated. The white crystal was pulverized, and was washed in ether. The pulverized white crystal was dried at 30 degrees in centigrade for 6 hours by using a low-pressure drier. 5.15 grams of 2-oxo-3,3-dimethylbutyl-thiacyclopentanium bromide was obtained. The yield was 75.0%.

Aufarbeitung

  1. customwhite crystal was precipitated
  2. filtrationwas filtrated
  3. washwas washed in ether
  4. customThe pulverized white crystal was dried at 30 degrees in centigrade for 6 hours

Quellen und Nachweise

ORD-Eintrag
ord-6edaecb22a8f4b71b53e7e8dd3d76215
Quelldatensatz
uspto-grants-2003_10
Patentnummer
US06638685B2

Verknüpfte Notizen

Wird geladen…