HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrogen Peroxide → 1-(2-Hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidin-4-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrogen Peroxide | HCID 784 | — |
| Edukt | tert-Butanol | HCID 6386 | — |
| Edukt | Sodium Sulfite | HCID 24437 | — |
| Edukt | 1-Hydroxy-2,2,6,6-tetramethyl-4-oxopiperidine | HCID 98642 | — |
| Produkt | 1-(2-Hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidin-4-one | HCID 21885057 | — |
Reaktionsschritte
Aqueous hydrogen peroxide is added to a mixture of 1-oxyl-2,2,6,6-tetramethylpiperidin-4-one and ferrous chloride in tert-butyl alcohol at 30-60° C. Excess peroxide is decomposed with aqueous sodium sulfite. The organic layer is concentrated and the residue is purified by flash chromatography to afford the desired 1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidin-4-one.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06638997B2 |
| Quelldatensatz | uspto-grants-2003_10 |
| ORD ID | ord-c25c76894873411da9bbc7f4b2a9d3e2 |
| Quellennotiz | uspto-grants-2003_10 |