HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Glyceraldehyde → Benzyl 4,5-dihydroxy-2-pentenoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Glyceraldehyde | HCID 751 | — |
| Edukt | (Benzyloxycarbonylmethyl)triphenylphosphonium bromide | HCID 11214019 | — |
| Lösungsmittel | 1,2-Epoxybutane | HCID 7834 | — |
| Produkt | Benzyl 4,5-dihydroxy-2-pentenoate | HCID 54529065 | — |
Reaktionsschritte
A mixture of DL-glycerinaldehyde (4.5 g, 50 mmole) and (benzyloxycarbonylmethyl)-triphenyl-phosphoniumbromide (24.57 g, 50 mmole) in 100 ml 1,2-epoxybutane was refluxed overnight. The mixture was evaporated under vacuum and the product was isolated by silica gel column chromatography. Yield: 8 g=71%
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06458772B1 |
| Quelldatensatz | uspto-grants-2002_10 |
| ORD ID | ord-bf93b888e5ab4bcd9be5e6dda82bab73 |
| Quellennotiz | uspto-grants-2002_10 |