2-chloro-6-[(3-methyloxetan-3-yl)methyl]-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-({6-[(3-methyloxetan-3-yl)methyl]-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl}amino)thiophene-3-carboxamide

Reaktionsgleichung

[Cl:22][c:23]1[cH:24][cH:25][c:26]2[c:27]([n:28]1)[CH2:29][N:30]([CH2:33][C:34]1([CH3:38])[CH2:35][O:36][CH2:37]1)[C:31]2=[O:32].[NH2:1][c:2]1[s:3][c:4](-[c:10]2[c:11]([F:21])[cH:12][c:13]([C:17]([CH3:18])([CH3:19])[OH:20])[cH:14][c:15]2[F:16])[cH:5][c:6]1[C:7](=[O:8])[NH2:9]>>[NH:1]([c:2]1[s:3][c:4](-[c:10]2[c:11]([F:21])[cH:12][c:13]([C:17]([CH3:18])([CH3:19])[OH:20])[cH:14][c:15]2[F:16])[cH:5][c:6]1[C:7](=[O:8])[NH2:9])[c:23]1[cH:24][cH:25][c:26]2[c:27]([n:28]1)[CH2:29][N:30]([CH2:33][C:34]1([CH3:38])[CH2:35][O:36][CH2:37]1)[C:31]2=[O:32]