Phosgene → 1-Isocyanato-3-nitroadamantane

HRID 992166Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 992166
[C:1](Cl)(Cl)=[O:2].[NH2:5][C:6]12[CH2:15][CH:10]3[CH2:11][CH:12]([CH2:14][C:8]([N+:16]([O-:18])=[O:17])([CH2:9]3)[CH2:7]1)[CH2:13]2>C1(C)C=CC=CC=1>[N:5]([C:6]12[CH2:13][CH:12]3[CH2:11][CH:10]([CH2:9][C:8]([N+:16]([O-:18])=[O:17])([CH2:14]3)[CH2:7]1)[CH2:15]2)=[C:1]=[O:2]

Komponenten

4

Edukt 2

HCID 6371PhosgeneHCID 184104831-Amino-3-nitroadamantane

Produkt 1

HCID 132376841-Isocyanato-3-nitroadamantaneAusbeute 90 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

10 mmole of 1-amino-3-nitroadamantane obtained by the method of Example 66 was dissolved in toluene (100 ml). To the resultant solution, 12 mmole of phosgene was added at the room temperature and stirred for 6 hours. As a result, The conversion of 1-amino-3-nitroadamantane was 99%, and 1-isocyanato-3-nitroadamantane (yield 90%) was formed.

Quellen und Nachweise

ORD-Eintrag
ord-7dcf062a33334c4996fd91fea700d3d8
Quelldatensatz
uspto-grants-2002_10
Patentnummer
US06468487B1

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