HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrazine → 4-[6-(3-Amino-propyl)-pyridin-3-yl]-butyl amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrazine | HCID 9321 | — |
| Edukt | 2-(3-{5-[4-(1,3-Dioxo-isoindol-2-yl)-butyl]-pyridin-2-yl}-propyl)-isoindole-1,3-dione | HCID 18408985 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 4-[6-(3-Amino-propyl)-pyridin-3-yl]-butyl amine | HCID 18408986 | 111,6% |
Reaktionsschritte
A mixture of 3-4 (14 g, 30.7 mmol) and hydrazine (5 mL) in ethanol (500 mL) was heated at reflux for 5 hours. The mixture was cooled and concentrated to ⅓ volume, diluted with 300 mL MTBE, and filtered. The filtrate was concentrated to give 7.1 g of 3-5 as a brown oil, contaminated with a small amount of phthalhydrazide.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06472403B2 |
| Quelldatensatz | uspto-grants-2002_10 |
| ORD ID | ord-165f3f74c3344296a55b0036b226de24 |
| Quellennotiz | uspto-grants-2002_10 |